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Ray David Owen : ウィキペディア英語版
Ray David Owen

Ray David Owen (October 30, 1915 – September 21, 2014) was a teacher and scientist whose discovery of unusual, “mixed,” red blood cell types in cattle twins in 1945 launched the fields of modern immunology and organ transplantation.〔Svitil, Kathy, ("Remembering Ray D. Owen (1915-2014)" ), California Institute of Technology News, 9/23/2014〕 〔Mitchell, Bob, ("In memoriam: Ray D. Owen discovered immune tolerance, paved the way for organ transplantation" ), University of Wisconsin-Madison Department of Communications, 9/26/2014〕〔Brent, Leslie, "Ray David Owen (1915-2014): Geneticist and Immunologist. A Tribute to a True Pioneer", ''Transplantation'', Volume 98, Number 12〕〔Cancro, Michael P., December 2014, ("Ray D. Owen, 1915-2014" ), ''Nature Immunology'', Volume 15, Number 12〕 Owen’s 1945 findings were published in the journal ''Science''.〔Owen RD, 1945, "Immunogenetic consequences of vascular anastomosis between bovine twins", ''Science'', 102: 400〕 This observation demonstrated that self was “learned” by the immune system during development and paved the way for research involving induction of immune tolerance and early tissue grafting.〔 〔 When Frank Macfarlane Burnet and Sir Peter Brian Medawar were awarded their 1960 Nobel Prize in Physiology or Medicine for the discovery of acquired immunological tolerance, Owen was not mentioned in the prize. However, in a letter to Owen, Medawar stated that he believed Owen should have also been included in the prize.〔Crow, James F., November 1996, "A Golden Anniversary: Cattle Twins and Immune Tolerance, ''Genetics'', 144: 855-859〕 Owen also led the successful effort to admit women as California Institute of Technology (or Caltech) undergraduates.〔
== Early life and education ==
Owen was born and raised on a dairy farm in Genesee, Wisconsin, on October 30, 1915.〔 He attended school at the two-room Genesee State Graded School for eight years.〔Owen, Ray David, Interview by Rachel Prud’homme, Pasadena, California, October-November 1983, (Oral History Project, California Institute of Technology Archives ), Retrieved 1/7/2014〕 He continued his education at a high school in Waukesha, commuting the eight miles to and from school every day from his family’s farm.〔 In 1937 Owen received a BS in biology from Carroll University (then Carroll College). 〔 In 1941 Owen received a PhD in genetics from the University of Wisconsin–Madison, where he continued to work as a postdoctoral researcher and assistant professor for several years. It was during this time that Owen conducted his seminal work in twin calves. In 1946 Owen moved to Pasadena, California, to join the biology department at Caltech as a Gosney Fellow.〔

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